Spravato® (esketamine) Nasal Spray for Treatment-Resistant Depression | Find a center near you

Get Rapid Relief with Spravato®

When antidepressants haven't worked, Spravato® may offer a different path. Find out if you're a candidate, or keep reading to learn more.

Spravato® is the only FDA-approved nasal spray for treatment-resistant depression.

Spravato® is an FDA-approved nasal spray for adults living with treatment-resistant depression (TRD) or major depressive disorder with suicidal ideation (MDSI). Administered under clinical supervision, it works through a different mechanism than standard antidepressants, and it's the only ketamine-based therapy covered by most major insurance plans.

What conditions can Spravato® treat?

Spravato® is specifically designed as a standalone treatment or alongside an oral antidepressant for adults who haven't found relief with traditional antidepressants.

Treatment-Resistant Depression (TRD)

Treatment-resistant depression happens if you have taken 2 or more oral antidepressants and still experience symptoms of depression.

Major Depressive Disorder with Suicidal Ideation (MDSI)

Severe clinical depression with recurring suicidal thoughts or actions.

Spravato® shows significant improvement in depression symptoms within 24 hours — and continues to demonstrate rapid improvement in symptoms at 4 weeks.

What does the Spravato® treatment process look like?

01
60 mins - telehealth
Consultation
Evaluation with one of our prescribers where they will determine eligibility.

02
Weeks 1-4
Induction
Two times a week in an in-person clinic.

03
Weeks 5-8
Optimization
Once a week in an in-person clinic.

04
Ongoing
Maintenance
Once a week in an in-person clinic.

Every session is administered and monitored by a Spravato®-trained clinician for your safety.

The Spravato®withMe program offers rebates to help cover eligible out-of-pocket costs. Based on your insurance benefits and deductible, eligible patients can receive assistance that reduces treatment expenses to as low as $10 per session.

Experience Spravato® in a Setting Built for Comfort

Spravato® sessions at Journey Clinical take place in a therapist's private office — not a large clinic or hospital setting. You'll be treated alongside a few other patients, in a calm, quiet environment designed to support your experience rather than distract from it.

Real Stories from Spravato® Patients

It's really like a veil had lifted [after Spravato]. I am in a better place now than I have been maybe ever. And I think that's an amazing gift.
Grace, CO
Some days I would just collapse in a fit of crying, on only 5 hours of sleep a week. With Spravato®, I was learning to love myself each and every session — and I'm really proud of where I am now.
Ben, NY
My symptoms were so severe I was laid off and couldn't socialize. Spravato® gave me hope — not just to get through the day, but to start over.
Karen, IL
I would sleep 18 to 20 hours a day and I truly hated myself. After starting Spravato®, I'm waking up neutral every day — and for me, that's everything.
Nicole, MO

Take the first step today.

Find a Journey Clinical Spravato® center near you and fill out the brief form on the center's profile to begin your path to relief.

Journey Clinical Spravato - Find a Spravato® Treatment Site

Spravato® is an FDA-approved treatment for treatment-resistant depression. Find a location below, click the site to see details, and submit the form to request care or refer a patient. Our team reaches out within 24-hours with next steps.

The Performance Sanctuary

Location:
Ballston Spa, NY
Accepted Insurance(s):
Aetna, Cigna, UnitedHealthcare, Optum
Site Clinician:
Rachel Colfer, PA-C
Site Therapist/Representative:
Rachel Moore, LCSW
Phone Number:
(914) 306-5174

Seaglass Healing

Location:
Stuart, FL
Accepted Insurance(s):
Aetna, Florida Blue, Blue Cross Blue Shield (BCBS), Cigna, Curative, UnitedHealthcare, Optum, UMR
Site Clinician:
María Clara Restrepo, PMHNP
Site Therapist/Representative:
Amanda Allison, MSW, LCSW, LISW-S
Phone Number:
(914) 306-5174

Ironwood Therapeutic Wellness

Location:
Haslet, TX
Accepted Insurance(s):
Aetna, Blue Cross Blue Shield (BCBS), Cigna, Curative, UnitedHealthcare, Optum, UMR
Site Clinician:
Shaina King, PMHNP-BC
Site Therapist/Representative:
Kailee Rubright, LCSW
Phone Number:
(914) 306-5174

Midwifing the Mind

Location:
Charlottesville, VA
Accepted Insurance(s):
Aetna, Cigna, UnitedHealthcare, Optum, UMR
Site Clinician:
Lynn Wolf, PMHNP
Site Therapist/Representative:
Lynn Wolf, PMHNP
Phone Number:
(914) 306-5174

Journey Clinical Spravato - Brooklyn

Location:
Brooklyn, NY
Accepted Insurance(s):
Aetna, Cigna, UnitedHealthcare, Optum, UMR
Site Clinician:
Gillian Dougherty
Site Therapist/Representative:
Will Vaxmonsky
Phone Number:
(914) 306-5174

Journey Clinical Spravato - Dallas

Location:
Dallas, TX
Accepted Insurance(s):
Aetna, Blue Cross Blue Shield (BCBS), Cigna, Curative, UnitedHealthcare, Optum, UMR
Site Clinician:
Lynn Nguyen
Site Therapist/Representative:
Will Vaxmonsky
Phone Number:
(914) 306-5174

Journey Clinical Spravato - Superior

Location:
Superior, CO
Accepted Insurance(s):
Aetna, Cigna, UnitedHealthcare, Optum, UMR, Anthem
Site Clinician:
Shannon Mostafiz
Site Therapist/Representative:
Will Vaxmonsky
Phone Number:
(914) 306-5174

Francesca Aborn Spravato

Location:
New York, NY
Accepted Insurance(s):
Aetna, Cigna, UnitedHealthcare, Optum, UMR
Site Clinician:
Gillian Dougherty
Site Therapist/Representative:
Francesca Aborn, LCSW
Phone Number:
(914) 306-5174

Behavioral Medicine Institute, PC

Location:
Knoxville, TN
Accepted Insurance(s):
Aetna, Cigna, UnitedHealthcare, Optum, UMR
Site Clinician:
Maggie Quinn
Site Therapist/Representative:
Jacob Joseph Levy, Ph.D., HSP; Licensed Psychologist, Health Service Provider
Phone Number:
(914) 306-5174